2012年 EFNS-ENS 痴呆相关疾病诊疗指南

2012-08-14 欧洲神经科学协会联盟 European Journal of Neurology, 2012, 19(9): 1159–1179

中文标题:

2012年 EFNS-ENS 痴呆相关疾病诊疗指南

英文标题:

EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia

发布日期:

2012-08-14

简要介绍:

Background and objectives: The last version of the EFNS dementia guidelines isfrom 2007. In 2010, the revised guidelines for Alzheimer’s disease (AD) were published.The current guidelines involve the revision of the dementia syndromes outsideof AD, notably vascular cognitive impairment, frontotemporal lobardegeneration, dementia with Lewy bodies, corticobasal syndrome, progressive supranuclearpalsy, Parkinson’s disease dementia, Huntington’s disease, prion diseases,normal-pressure hydrocephalus, limbic encephalitis and other toxic and metabolicdisorders. The aim is to present a peer-reviewed evidence-based statement for theguidance of practice for clinical neurologists, geriatricians, psychiatrists and otherspecialist physicians responsible for the care of patients with dementing disorders. Itrepresents a statement of minimum desirable standards for practice guidance.Methods: The task force working group reviewed evidence from original researcharticles, meta-analyses and systematic reviews, published by June 2011. The evidencewas classified (I, II, III, IV) and consensus recommendations graded (A, B, or C)according to the EFNS guidance. Where there was a lack of evidence, but clear consensus,good practice points were provided.Results and conclusions: New recommendations and good practice points are madefor clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography,cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis,treatment of behavioural and psychological symptoms in dementia, legal issues,counselling and support for caregivers. All recommendations were revised as comparedwith the previous EFNS guidelines. The specialist neurologist together withprimary care physicians play an important role in the assessment, interpretation andtreatment of symptoms, disability and needs of dementia patients.

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