肌萎缩侧索硬化-话题@MedSci

#肌萎缩侧索硬化#

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肌萎缩侧索硬化

2020-05-29

yangchou (审核中...)

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全文收起 #肌萎缩侧索硬化# 肌萎缩侧索硬化症（ALS）是一种进行性神经退行性疾病，其特征是上下运动神经元丧失，最终导致呼吸衰竭。虽然ALS的发病高峰期（AAO）女性为45-49岁，男性为55-59岁，但任何年龄的人都可能受到影响。ALS的AAO是一个关键表型特征，与运动和认知表型的变化、疾病进展、预后和生存有关。识别影响ALS AAO的风险因素可以帮助更好地了解疾病病因，并为患者和临床医生提供临床指导。然而，ALSAAO异质性背后的机制很复杂，仍然鲜为人知。

2023-11-15发表于浙江省

(审核中...)

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美国#FDA#宣布，批准#Relyvrio#（#苯丁酸钠#和#牛磺酸二醇#口服固定剂量配方）上市，用于治疗#肌萎缩侧索硬化#（ALS）。

FDA批准肌萎缩侧索硬化（ALS）复方药物Relyvrio，5年来首个新药

2022-09-30

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

肌萎缩侧索硬化症：症状与体征、病因、流行病学、诊断和治疗

2022-08-30

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:苯丁酸钠/牛磺酸钠对肌萎缩侧索硬化患者气管切开/无通气生存和住院的影响

2022-06-24

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JAMA：肌内神经束内 TDP-43 积聚可能是肌萎缩侧索硬化患者的一种新型诊断生物标志物。

2022-05-30

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：C9orf72相关额颞叶痴呆和肌萎缩侧索硬化症的脑脊液生物标记物分析方法的开发

2022-04-06

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：伴TARDBP突变的肌萎缩侧索硬化症患者的18-氟脱氧葡萄糖正电子发射断层扫描结果改变

2022-04-04

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

Nat Med：反义寡核苷酸沉默FUS表达可治疗肌萎缩侧索硬化症

2022-01-28

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：基于患者偏好的肌萎缩侧索硬化临床试验终点研究

2022-01-07

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：神经丝、CHIT1、YKL-40和MCP-1在肌萎缩侧索硬化患者中的预后关系

2022-01-04

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

Lancet Neurol：左西孟旦有望改善肌萎缩侧索硬化症呼吸衰竭？

2021-10-25

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:肌萎缩侧索硬化症胸椎型变异的分型

2021-10-23

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：脑MRI和神经系统检查对肌萎缩侧索硬化症患者上运动神经元变性的敏感性

2021-10-21

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:GBA基因变异影响肌萎缩侧索硬化症患者的认知状态

2021-10-04

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：较高的血液高密度脂蛋白和载脂蛋白A1水平与肌萎缩侧索硬化风险降低相关

2021-09-25

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP：低代谢状态：肌萎缩侧索硬化预后较好的预测因子

2021-08-16

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

Nat Med：过量鞘脂合成会引起儿童肌萎缩侧索硬化

2021-06-03

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:肌萎缩侧索硬化症系统基因筛查的价值

2021-03-18

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:肌萎缩侧索硬化症认知损害的危险因素：系统回顾和荟萃分析

2021-03-11

liuyong2984 (审核中...)

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#肌萎缩侧索硬化#

JNNP:肌萎缩侧索硬化症系统基因筛查的意义

2021-02-21

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